Her commitment for the music of today led her to become a soloist of the Ensemble intercontemporain directed by Pierre Boulez, with whom she premiered some of the greatest masterpieces of the 20th century, like his Anthèmes for solo viola at the Avignon Festival, and recorded Le Marteau sans Maître for Deutsche Grammophon. She premiered Anthèmes 2 for solo viola and electronics at the Philharmonie de Paris in 2021, as the culmination of her collaborating years with Pierre Boulez.

She has also closely collaborated with the great composers of the second half of the 20th century, such as György Kurtág, Peter Eötvös, George Benjamin and Marco Stroppa, as well as with composers of the new generation, premiering many of their works.

She is highly active on the French and international music scenes and is regularly invited to perform as a soloist or chamber musician in numerous concert seasons and festivals. She has been designated a "Génération Spedidam" Classical Artist for the next three years (2022-2024).

As an eclectic, creative and inquisitive artist, Odile Auboin has developed an original approach to different repertoires, through an interdisciplinary approach that blends music with different forms of artistic expression, such as the visual arts, literature, improvisation and new technologies. She favours collaborative projects with other artists, whether they be solo musicians, as in l’Amour à trois temps (with Dana Ciocarlie and Pascal Contet), chamber music ensembles (the Antara trio, flute, viola and harp), actors (Dominique Frot, François Marthouret), improvisers (Vincent Segal, György Kurtág Jr) or performers in electronic and multimedia creation (Gilbert Nouno). Her latest collaborations have led her to explore the creation of immersive devices for artists and audiences (Schubert revisited -2023-, performances with Flashback).

She joined the Collège Contemporain, a group of composers, performers and musicologists, where she helps to develop collective projects for the transmission and creation of music, which she particularly promotes as an assistant professor at the Conservatoire National Supérieur de Musique et de Danse de Paris.